Association Between Headaches and Tinnitus in Young Adults: Cross-Sectional Study.

Abstract

To study the association between migraine and tinnitus in a large, cross-sectional study among students. Tinnitus has been associated with various pain syndromes, including headaches. However, prior studies were mainly conducted among elderly adults. Cross-sectional study among 5729 participants of the French internet-based Students Health Research Enterprise (i-Share) cohort. Health, personal and lifestyle habits, and socio-demographics characteristics as well as headache/migraine symptoms and tinnitus, were recorded in a standardized questionnaire based on self-reports. Logistic regression models were used to evaluate the association between the students' headache status and tinnitus. The 5729 participants had a mean age of 20.8 years (standard deviation 2.8 years), 75.4% were female, and 1645 reported migraine. An association was found between the students' headache status and tinnitus after adjustment for confounding variables. Tinnitus was reported by 8.9% of participants with migraine, 7.3% of patients with migraine without aura, and 10.8% of participants with migraine with aura. The adjusted odds ratios of tinnitus were 1.77 (95% confidence interval, 1.36-2.30) for migraine and 1.38 (0.98-1.92) for non-migraine headache. The association was stronger for students with migraine with aura (odds ratio = 2.10, 95% confidence interval 1.54-2.86) than for migraine without aura (odds ratio = 1.51, 95% confidence interval 1.09-2.07). We found an association between migraine and tinnitus among young individuals, which was strongest for the subgroup migraine with aura.