Abstract

Background: This study was designed to investigate the perceived relationship between body weight and depression risk in a Chinese population in Qingdao, China.Methods: A population-based cross-sectional survey was performed with 4,573 participants (between 35 and 74 years) from the year 2009 to 2012 in Qingdao, China. We applied the Zung self-rating depression scale to ascertain the level of depression in participants. The associations between different indicators of obesity [body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR)] and depression were assessed by logistic regression based on the Chinese criteria of obesity. Sensitivity analysis was done based on the Asian and WHO criteria of obesity.Results: The Zung scores for the 243 participants (5.2%) were over 45 and they were entitled as depression. Furthermore, multivariable logistic analyses revealed that being overweight [odds ratios (OR): 1.48, 95% confidence intervals [95% CI]: 1.08–2.03] and having abdominal obesity (WC category in Chinese criteria) (OR: 1.47, 95% CI: 1.08-2.00) were often associated with a higher risk for depression compared to normal weight subjects. Sensitivity analysis revealed that abdominal obesity (Asian criterion) (OR: 1.41, 95% CI: 1.03-1.91) was a significant risk factor for depression. Similarly, being overweight (WHO criterion) (OR: 1.39, 95% CI: 1.03-1.87) was an obvious risk factor for depression.Conclusion: Being overweight and having abdominal obesity (WC category) were found to be linked with a higher risk of depression. However, abdominal obesity (WHR category) was not associated with depression.

Highlights

  • Significant progress has been made in improving public health in the world; many serious health issues still need to be resolved such as depression and obesity

  • Multivariable logistic analyses revealed that being overweight [odds ratios (OR): 1.48, 95% confidence intervals [95% Confidence intervalsl (CI)]: 1.08–2.03] and having abdominal obesity (WC category in Chinese criteria) (OR: 1.47, 95% CI: 1.08-2.00) were often associated with a higher risk for depression compared to normal weight subjects

  • Sensitivity analysis revealed that abdominal obesity (Asian criterion) (OR: 1.41, 95% CI: 1.03-1.91) was a significant risk factor for depression

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Summary

Introduction

Significant progress has been made in improving public health in the world; many serious health issues still need to be resolved such as depression and obesity. The global prevalence of being overweight and obese was estimated to be 39% and 13% in adults aged 18 years and over in 2017, respectively [1]. In 2018, the World Health Organization (WHO) estimates that depression is seen to affect approximately 300 million people worldwide [2]. In China, the prevalence of obesity has been continuously increasing during the last few decades [3,4,5]. Depression is frequently diagnosed at public and private clinics. Approximately 26 million people are struggling with symptoms of mild depression annually in China [6]. This study was designed to investigate the perceived relationship between body weight and depression risk in a Chinese population in Qingdao, China

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