Abstract
BackgroundPrimary informal caregivers provide a substantial amount of the care and support for persons with Alzheimer’s disease (AD). This review aims to investigate the association between the quality of life (QoL) of primary informal AD caregivers and the level of care that these caregivers provide to persons with AD.MethodsStudies involving primary informal caregivers of persons with AD will be included in the review. These studies will be required to focus on the care that caregivers provide for their loved ones. The primary outcome is level or quality of care. The main independent variable is caregiver QoL. In addition to QoL, we will include studies that examine other independent variables that are considered to be important components of QoL. These variables include social support, caregiver burden, caregiver wellbeing, and caregiver depression.We will search Medline-OVID, Embase-OVID, Cochrane Central-OVID, and PsycINFO-OVID from inception onwards. Two raters will independently screen each article using pre-established inclusion/exclusion criteria. Screening will take place at two levels: title and abstract, and full text. Conflicts will be resolved by discussion or by a third reviewer. We will assess the risk of bias of each included study using standardized quality assessment tools for specific types of designs. A narrative synthesis method will be used to describe our findings. Quantitative summary and meta-analysis will be conducted if appropriate. We will employ GRADE to evaluate the strength of the evidence in this review.DiscussionResults of this systematic review will show whether and how caregiver QoL is related to the level of care that caregivers provide to persons with AD.
Highlights
Primary informal caregivers provide a substantial amount of the care and support for persons with Alzheimer’s disease (AD)
This review aims to investigate the association between the quality of life (QoL) of primary informal AD caregivers and the level of care that these caregivers provide to persons with AD
The systematic review described in this protocol follows the PRISMA statement [12]
Summary
Primary informal caregivers provide a substantial amount of the care and support for persons with Alzheimer’s disease (AD). This review aims to investigate the association between the quality of life (QoL) of primary informal AD caregivers and the level of care that these caregivers provide to persons with AD. Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive declines in cognitive and functional abilities. Symptoms often begin with memory loss and progress to an inability to perform basic activities of daily living (for example, bathing and eating) [1]. The estimated prevalence of AD in the Canadian population aged 65 years or over is 300,000 persons [2]. 40,000 Canadians develop the disease annually [3]. Projections suggest the total number of Canadians with AD could rise to 509,000 in 2031 [3,4].
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