Abstract
BackgroundThe balance of vaginal microecology is closely related to human papillomavirus (HPV) infection and cervical lesions. This study aims to investigate the relationship between bacterial vaginosis (BV) and HPV infection.MethodsIn total, 1,310 individuals from the National Health and Nutrition Examination Survey (NHANES, 2003–2004) were included in this study. Logistic regression and subgroup analyses were used to examine the association between BV and HPV infection.ResultsA significant positive association was observed between BV and HPV infection in women after adjustment for other confounders (OR = 1.47, 95% confidence interval [CI]: 1.15–1.88). In subgroup analyses, we have found this positive correlation was most prominent among Mexican Americans (OR = 1.83, 95% CI: 1.08–3.08) and non-Hispanic blacks (OR = 1.81, 95% CI: 1.08–3.04).ConclusionsThis cross-sectional study demonstrated a positive association between BV and HPV infection in women.
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