Abstract

Objectives: This paper reports on the findings of a population-based study to evaluate the relationship between atmospheric fine particulate matter (PM2.5) levels and hospital admissions for chronic obstructive pulmonary disease (COPD) in southwestern Taiwan over a three-year period, 2008–2010. Methods: Data on hospital admissions for COPD and PM2.5 levels were obtained from the National Health Insurance Research database (NHIRD) and the Environmental Protection Administration from 2008 to 2010, respectively. The lag structure of relative risks (RRs) of hospital admissions for COPD was estimated using a Poisson regression model. Results: During the study period, the overall average hospitalization rate of COPD and mean 24-h average level of PM2.5 was 0.18% and 39.37 μg/m3, respectively. There were seasonal variations in PM2.5 concentrations in southwestern Taiwan, with higher PM2.5 concentrations in both spring (average: 48.54 μg/m3) and winter (49.96 μg/m3) than in summer (25.89 μg/m3) and autumn (33.37 μg/m3). Increased COPD admissions were significantly associated with PM2.5 in both spring (February–April) and winter (October–January), with the relative risks (RRs) for every 10 μg/m3 increase in PM2.5 being 1.25 (95% CI = 1.22–1.27) and 1.24 (95% CI = 1.23–1.26), respectively, at a lag zero days (i.e., no lag days). Lag effects on COPD admissions were observed for PM2.5, with the elevated RRs beginning at lag zero days and larger RRs estimates tending to occur at longer lags (up to six days, i.e., lag 0–5 days). Conclusions: In general, findings reveal an association between atmospheric fine particulate matter (PM2.5) and hospital admissions for COPD in southwestern Taiwan, especially during both spring and winter seasons.

Highlights

  • Chronic obstructive pulmonary disease (COPD) has been reported to be a leading cause of morbidity and mortality and will become the third leading cause of death by 2030 worldwide [1].chronic obstructive pulmonary disease (COPD) results in a substantial economic burden on healthcare services [2,3]

  • There was a mean of 8.73 daily hospital admissions for COPD in southwestern Taiwan over the study period

  • The present study investigated the effects of atmospheric fine particles (PM2.5 ) on hospital admissions for COPD in Southwestern Taiwan

Read more

Summary

Introduction

Chronic obstructive pulmonary disease (COPD) has been reported to be a leading cause of morbidity and mortality and will become the third leading cause of death by 2030 worldwide [1]. COPD results in a substantial economic burden on healthcare services [2,3]. Lung Blood Institute (NHLBI) estimated that the direct cost of COPD was $29.5 billion in the U.S. in 2010 [2]. In Singapore, the average direct cost of COPD was $9.9 million per year from 2005 to. Several studies have reported that the morbidity and mortality rate of COPD is increasing in the Asia-Pacific regions [3,4,5]. In the Asia-Pacific, overall mortality and morbidity rates ranged

Objectives
Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call