Abstract

Apathy is a common symptom in idiopathic normal pressure hydrocephalus (iNPH). However, the neuroanatomical bases of apathy in iNPH has not been well examined. We assessed the relationship between improvement of apathy and change of regional cerebral blood flow (rCBF) after shunt surgery.

Highlights

  • Apathy is a common symptom in idiopathic normal pressure hydrocephalus

  • We recruited 20 idiopathic normal pressure hydrocephalus (iNPH) patients who had apathy before shunt surgery. They were tested about apathy with Neuropsychiatric Inventory (NPI) and cognitive function with Mini-mental State Examination (MMSE) and Frontal Assessment Battery (FAB)

  • A significant correlation was found between the changes of apathy score in NPI and score of FAB

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Summary

Introduction

Apathy is a common symptom in idiopathic normal pressure hydrocephalus (iNPH). The neuroanatomical bases of apathy in iNPH has not been well examined. We assessed the relationship between improvement of apathy and change of regional cerebral blood flow (rCBF) after shunt surgery

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