Abstract
Excessive aortopulmonary collateral (APC) flow is hypothesized to negatively affect outcome after a Fontan operation. Lack of an accurate and readily applied technique to measure APC flow has hindered research on this issue.
Highlights
Excessive aortopulmonary collateral (APC) flow is hypothesized to negatively affect outcome after a Fontan operation
APC flow/body surface area (BSA) was not associated with age at cardiac MRI (CMR), age at Fontan, history of systemic-pulmonary artery shunt (n=61) or bidirectional Glenn shunt (n=35), history of catheter-based occlusion of APCs (n=10), congestive heart failure (n=21), atrial or ventricular arrhythmias (n=54), >mild atrioventricular valve regurgitation (n=10), ejection fraction, and peak oxygen consumption (VO2) on maximal exercise stress test (n=43) within 1 year of CMR
In this cohort of late survivors of a Fontan operation, APC flow measured by CMR comprised a significant proportion of cardiac output and was associated with larger BSA-adjusted ventricular volume
Summary
Excessive aortopulmonary collateral (APC) flow is hypothesized to negatively affect outcome after a Fontan operation. Lack of an accurate and readily applied technique to measure APC flow has hindered research on this issue. Purpose We used a recently described cardiac MRI (CMR) method to quantify APC flow in a large cohort of late Fontan survivors, and evaluate its relationship with clinical outcomes
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