Abstract
OBJECTIVE: MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate the abundance and translation of mRNAs. Recent data indicate the importance of miRNAs during development, including our previous report of six altered miRNA profiles in blastocysts derived from infertile patients. This study examined expression of miRNAs, their target genes and the miRNA biogenesis pathway in human blastocysts derived from patients with polycystic ovaries (PCO) and male factor infertility (MF).
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