Abstract
Purpose: Hypothyroidism can commonly cause myopathy, characterized by myalgia and weakness, affecting almost 80 percent of patients. This myopathy may be important in the course of knee osteoarthritis (KOA), in which thigh muscles play an essential role in the incidence and progression of the diseases. Despite that hypothyroidism and KOA are very common and frequently coexist in the elderly population, no conclusive evidence is available regarding the possible association of hypothyroidism with thigh muscle changes.
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