Assisted ventilation prior to umbilical cord clamping: Potential benefits, challenges, and research studies

Abstract

Delayed cord clamping (DCC) is beneficial for many infants, and the American College of Obstetrics and Gynecology recommends at least 30-60 seconds of DCC for both term and preterm vigorous infants. For newly born infants that are not vigorous, some evidence in animal models suggests that providing assisted ventilation prior to cord clamping (V-DCC) leads to a more stable transition of cerebral, pulmonary and systemic circulation and oxygenation and may confer not only short-term physiologic benefits but perhaps also improvement in clinically important outcomes. This review is based around 7 questions to help the reader understand the physiologic underpinnings and challenges of V-DCC as well as the published and ongoing research studies aimed at determining whether V-DCC is beneficial for preterm or term infants.