Abstract
Objective To determine the outcome of women with early-stage ovarian malignancies who subsequently underwent assisted reproductive technologies (ART). Design Retrospective study. Setting Academic assisted reproductive technology program. Patient(s) Four infertile women who were previously diagnosed with early-stage ovarian malignancies. Intervention(s) Controlled ovulation hyperstimulation, IVF, and/or gamete intrafallopian transfer treatments using clomiphene citrate and/or gonadotropins. Main outcome measure(s) Development of tumor recurrence and disease-free interval. Result(s) All four women remain free of disease for up to 15 years after treatment. Three of the four women achieved pregnancy. Conclusion(s) In patients with early-stage ovarian malignancies, conservative therapy followed by ovarian stimulation for assisted reproduction is an acceptable strategy.
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