Abstract
Assisted hatching (AH) may optimize embryo implantation by opening the zona pellucida to enhance embryo attachment to the endometrium. AH has been employed for a variety of conditions that may predispose the embryo to impaired implantation, diminished oocyte quality leading to poor embryos, cryopreserved embryos, and repeat implantation failure. It has been suggested that AH be used in cycles where oocytes have been vitrified, due to possible physiologic changes in the zona induced by vitrification/warming1,2.
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