Abstract
Treatment of early-stage cervical cancer can be associated with a normal life expectancy but most treatments either castrate the patient or render her sterile. Assisted reproduction technologies have now provided options that may allow these women to become genetic parents. Superovulation, in-vitro fertilisation (IVF), and gestational surrogacy can be carried out before or after anticancer treatment provided the ovaries are spared and are functional. Otherwise, ovarian biopsy and cryopreservation may be done before bilateral oophorectomy, chemotherapy, or radiotherapy. We have treated seven women with IVF and gestational surrogacy (see table). Table 1Data for patients and surrogates Median Minumum Maximum surrogates' age (yr) 28·5 26 39 Surrogates' previous pregnancies 2 2 4 Commissioning mothers' age (yr) 37 25 41 Commissioning mothers' previous pregnancies 1 0 3 Interval since hysterectomy (yr) 2 0 11 Ampoules of gonadotropin used 49 22 96 Number of oocytes retrieved 9 6 15 Number of IVF treatment cycles 1 1 3 Open table in a new tab
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