Assessment the association between liver cancer incidence and mortality rate with human development index in the European countries in 2012

Abdollah Mohammadian-Hafshejani,Fatemeh Allah Bakeshei,Hamid Salehiniya,Mahdi Mohammadian,Mohammad Aryaie,Mujtaba Shuja,Pezhman Bagheri,Salman Khazaei,Sarah Islamie Farsani

doi:10.15419/bmrat.v4i03.156

Abstract

Background: Liver Cancer (LC) is one of the most common cancers in the worldwide. This cancer is considered as the fifth most common cancer in male and the ninth most common cancer in female. However, socioeconomic factors and morbidity and mortality of cancer are linked by sophisticated and flexible pathways. We were investigated the association between incidence and mortality of LC with the Human Development Index (HDI) in European countries in 2012. Methods: This study was an ecologic study in European countries for assessment the correlation between Age-Specific Incidence Rate (ASIR) and Age-Specific Mortality Rate (ASMR) of LC with HDI and its details including: Life expectancy at birth, Mean years of schooling and Gross National Income (GNI) per capita. We used of Pearson correlation method for appraisement the association between HDI and its components with ASIR and ASMR. Data of study was analyzed by SPSS15 statistical analysis software; the significance level of the tests was considered P˂0.05. Results: Generally in 2012, European countries have recorded 63,462 new cases of LC, crude rate was 8.6 and ASIR was 4.3 per 100,000. On the other hand in Europe countries in 2012, 62,191 cases of deaths were occurred due to LC, crude rate was 8.4 and ASMR was 3.9 per 100,000. Strong positive Correlation was observed between ASIR and ASMR (r = 0.848; P ≤ 0.001). HDI have weak negative correlation with ASIR of LC (r = - 0.194; P = 0.230), and strong negative correlation with ASMR of LC(r= - 0.515; P = 0.001). Conclusion: Increase in the human development index was associated with reduce in incidence and mortality of LC.

Highlights

Liver cancer (LC) is one of the most common cancers in the worldwide (Wei et al, 2014)
In the study that conducted in Asian countries about relationship of incidence and mortality of Liver Cancer (LC) with Human Development Index (HDI), negative correlation was observed between Age-Specific Incidence Rate (ASIR) and Age-Specific Mortality Rate (ASMR) with HDI, But this relationships wasn’t significant (Mohammadian et al, 2015)
According to our information, no study has been done still regarding the association between the ASIR and ASMR of LC with HDI in European countries; in this study we investigate the association between incidence and mortality of LC with HDI in European countries in 2012

Summary

Introduction

Liver cancer (LC) is one of the most common cancers in the worldwide (Wei et al, 2014). In the study that conducted in Asian countries about relationship of incidence and mortality of LC with HDI, negative correlation was observed between ASIR and ASMR with HDI, But this relationships wasn’t significant (Mohammadian et al, 2015). This study was an ecologic study in European countries for appraisal the relationship among Age-Specific Incidence Rate (ASIR) and Age-Specific Mortality Rate (ASMR) with Human Development Index (HDI) and its details including: Life expectancy at birth, average years of schooling and Gross National Income (GNI) per capita. Details of Methods for estimate the Age-specific incidence rate (ASIR) and Agespecific mortality rate (ASMR) in GLOBOCAN project have been provided in previous reports (Ferlay et al, 2010; Ferlay et al, 2015; Foulkes and Cooney, 2010; Pakzad et al, 2015b; Pakzad et al, 2016). Statistical analyses were performed using SPSS (Version 16.0, SPSS Inc.)

Results

Discussion

Conclusion