Abstract

Objective:Medications are generally administered by either the enteric or parenteral route. With parenteral administration, intramuscular (IM) is the preferred approach because it increases the bioavailability of the drug, acts more quickly than the enteric route. The aim of this study was to determine the rate of true dorsogluteal intramuscular drug injection and to determine the causes for application failures in practice by ultrasonography (US).Methods:The study was conducted from May 1 to May 30, 2017 in Giresun University Education and Research Hospital, Giresun, Turkey. We examined 60 patients who were administered dorsogluteal IM injection with a 38.1mm length needle. After the injection, localization of medications (whether intramuscular or subcutaneous adipose tissue [SAT]) was evaluated by Ultrasound.Results:Female/male ratio of the patients was 27/33, with a mean age of 39.78±2.16 years. Obese/normal weight ratio was 20/40. The mean dorsogluteal area SAT thickness of obese and normal weight patients were 32.34±2.17 mm and 20.85±1.20 mm, respectively. In 23 of the patients, IM injected drug was observed in the SAT, while it was observed in the IM area in 37 patients. Medication was observed in IM area in 37 of 50 patients who dorsogluteal region SAT thickness was appropriate (SAT thickness lower than 33.1mm) for IM injection while it was seen in SAT area in 13 patients.Conclusions:SAT thickness values are important if IM drug injection is to be administered correctly. Unsuccessful IM injections may be seen even in patients with appropriate SAT thicknesses.

Highlights

  • Medications are generally administered by either the enteric or parenteral route

  • The patients were classified into 1 of 2 groups according to body mass index (BMI) values: obese (n = 20), those with a BMI higher than 25, and normal weight (n = 40), those with a BMI lower than 25

  • The subcutaneous adipose tissue (SAT) thickness at the gluteal site and waist circumference were statistically higher than the normal weight group (p < 0.05)

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Summary

Introduction

Pak J Med Sci July - August 2019 Vol 35 No 4 www.pjms.org.pk 1132 gluteal region is absorbed almost completely and reaches the target site through the vena cava inferior without entering the enterohepatic cycle. This ideal description of administration may not always be possible in clinical practice. This means that in patients with thick adipose tissue, it is likely that an injection will be administered into the subcutaneous adipose tissue (SAT) rather than IM.[1,4]

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