Assessment on the evaluation of corneal endothelial cell morphology and cell count in cataract with pseudoexfoliation

Abstract

To assess the cell morphology & evaluate corneal endothelial cell count in patients suffering from cataract with pseudoexfoliation (PEX).A cross-sectional study was planned and conducted in 40 eyes of patients, corneal endothelial cell density (CD), central corneal thickness (CCT) and coefficient of variation (CV) & percentage of hexagonal cells (6A) in cell size were assessed with application of specular microscopeThe mean age of patients with cataract & PEX was 68.5 years. 58% were males. Lower CD was found in 40% patients of 50-59 years & 60% patients 60-69 years. Patients above 70 years had normal CD for age. 6A was low in 90% of PEX corneas. Abnormal CV was seen in 67.5% patients. CCT, CD & 6A were lower in PEX glaucoma compared to PEX. Our study confirms the existence of quantitative and qualitative abnormalities in corneal endothelial cells with PEX especially when IOP is high.