Abstract
The effect of protease inhibitor used in treatment of HIV patients leading to abnormally increased Uric acid level was the focus of this research.100 HIV positive patient on Medication (protease inhibitor) and 100 HIV positive patients not on Medication (control) was investigated for Uric acid levels using Fortress Reagent Kit. The mean Uric acid level of HIV Patients on medication was 385.16mmol/l in males and 381.06mmol/l in females respectively, while mean Uric acid level of HIV Patients not on medication was 336.27mmol/l and 321.6mmol/l for male and female controls respectively. Comparism of mean Uric acid levels of HIV Patients on Medication with those not on Medication (control) was statistically significant (p 0.05). Comparism between age groups within male and female not on medication was not statistically significant (p>0.05).Conclusion was that uric acid level be monitored in HIV patients on medication (protease inhibitor) as treatment progresses since high uric acid level has been associated with gout as well as kidney stone formation.
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