Abstract

Directly observed therapy short course (DOTS) is a strategy in which a trained healthcare worker or a designated individual provides the prescribed antituberculous drugs and watches the patient to ensure the patient is taking each dose. The objective of this work was to study tuberculosis situation in Cairo governorate from 2006 to 2012 after application of DOTS. This was a retrospective clinical cohort study carried out at the Cairo governorate. Percentages of cure and complete treatment were 61.6 and 20.4%, respectively. The incidence of failure, death, default, and transfer out decreased after DOTS (2.2, 4.5, 8.6, and 2.7, respectively). The introduction of DOTS in the Cairo governorate has led to a treatment success rate of 82% (nearly similar to the WHO target of ‘85%’).

Highlights

  • Tuberculosis (TB) remains to be a major global health problem

  • The latest estimates included in this report are that there were 8.6 million new TB cases in 2012 and 1.3 million TB deaths (1.0 million deaths among HIV-negative individuals and 0.3 million HIV-associated TB deaths)

  • Most of these TB cases and deaths occur among men, but the burden of disease among women is high [1]

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Summary

Introduction

Tuberculosis (TB) remains to be a major global health problem. It causes ill-health among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide, after the HIV. The latest estimates included in this report are that there were 8.6 million new TB cases in 2012 and 1.3 million TB deaths (1.0 million deaths among HIV-negative individuals and 0.3 million HIV-associated TB deaths). Most of these TB cases and deaths occur among men, but the burden of disease among women is high [1]. The resolution calls on governments to adapt and implement the strategy with high-level commitment and financing. It reinforces a focus within the strategy on serving populations highly vulnerable to infection and poor healthcare access, such as migrants [2]. Observed therapy short course (DOTS) is a strategy in which a trained healthcare worker or a designated individual provides the prescribed antituberculous drugs and watches the patient to ensure the patient is taking each dose

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