Abstract

This study was designed to recognize the sonographic features of interstitial lung diseases (ILD). Furthermore, the possible correlations of these features with the functional and radiological parameters of the disease were assessed. Forty-two patients with ILD were included; each patient underwent spirometry, Multi Detector CT chest (MDCT) and transthoracic sonography (TS). Fifteen healthy volunteers were also studied as controls. The sonographic features among ILD patients were B lines in 73.8% , abolished lung sliding in 23.8%, irregular and thickened pleura in 47.6%and 35.7% respectively and subpleural lesions in 38.1%.Increasing distance between the B lines was negatively correlated with both of Forced Vital Capacity % predicted , ground glass opacities and positively correlated with reticular opacities patterns on MDCT chest. TS can be used as an additional imaging method for assessment of ILD and as a marker to estimate the severity of disease.

Highlights

  • Chest ultrasonography has many uses, both diagnostic and interventional

  • The sonographic features among interstitial lung disease (ILD) patients were B lines in 73.8%, abolished lung sliding in 23.8%, irregular and thickened pleura in 47.6%and 35.7% respectively and subpleural lesions in 38.1%.Increasing distance between the B lines was negatively correlated with both of Forced Vital Capacity % predicted, ground glass opacities and positively correlated with reticular opacities patterns on Multi Detector Computed tomography (CT) chest (MDCT) chest

  • It was found that patients with ILD had a significant % of B lines compared with controls (73.8 vs.0%, P=0.001), whereas healthy controls had a significant percentage of A and O lines compared with ILD patients (66.7 vs.7.1%, P=0.002; 33.3 vs.9%, P=0.009, respectively)

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Summary

Introduction

Chest ultrasonography has many uses, both diagnostic and interventional. It is used in the diagnosis of diseases of the pleural space, such as pleural effusion, pleural thickening, pleural masses, and pneumothorax. It is used in the diagnosis of diseases caused by lung parenchymal lesions, such as pneumonia, lung abscesses, neoplasms, pulmonary embolism, and arteriovenous malformations [1]. High-resolution computed tomography (HRCT) should be considered the gold standard technique for the diagnosis of ILD, and many other noninvasive and invasive procedures concur in clinical practice to define and characterize ILD, such as chest radiography, laboratory and serological tests (e.g. angiotensinconverting enzyme and antinuclear antibodies), pulmonary function tests, bronchoscopy with bronchoalveolar lavage, and transbronchial lung biopsy [3]. TS can be useful in monitoring the course of the disease in patients with confirmed ILD ( avoiding unnecessary overload of radiation exposure)

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