Abstract
Background: Cone-Beam Computed Tomography (CBCT) with high-resolution parameters may provide an acceptable resolution for bone assessment. Objectives: The purpose of this study is to assess trabecular bone using two cone-beam computed tomography (CBCT) devices with high-resolution parameters in comparison to micro-computed tomography (µCT). Methods: Bone samples (n=8) were acquired from dry mandibles and scanned by two CBCT devices: 1) VV (Veraview R100, Morita; FOV 4x4, 75kV, 9mA, voxel size 0.125µm); and PR (Prexion 3D, Prexion; FOV 5x5, 90kV, 4mA, 37s, voxel size 108µm). Gold-standard images were acquired using µCT (SkyScan 1272; Bruker; 80kV, 125mA, voxel size 16µm). Morphometric parameters (BvTv- Bone Volume Fraction, BsBv- Trabecular specific surface, TbTh- Trabecular thickness and TbSp- Trabecular separation) were measured. Statistical analysis was performed within ANOVA, Spearman Correlation test and Bland-Altmann plots with a statistical significance level at p=0.05. Results: CBCT devices showed similar BvTv values in comparison to µCT. No statistical difference was found for BvTv parameters assessed by CBCT devices and µCT. BsBv values were underestimated by CBCT devices (p<0.01), whereas TbTh and TbSp values were overestimated by them (p<0.01). Positive correlations were found between VV and µCT measurements for BvTv (r2= 0.65, p=0.00), such as between PR and µCT measurements for TbSp (r2= 0.50, p=0.04). For BsBv measurements, PR was negatively correlated with µCT (r2= -0.643, p=0.01). Conclusion: The evaluated CBCT device was able to assess trabecular bone. However, bone parameters were under or overestimated in comparison to µCT.
Highlights
Introduction58 The Open Dentistry Journal, 2021, Volume 15 the method of choice to evaluate bone [10 - 12]
This study proposed to compare the trabecular bone assessment by two Cone-Beam Computed Tomography (CBCT) devices in regard to the μCT
A significant interaction was shown between scanners and bone type for BvTv, BsBv and Trabecular thickness (TbTh) values (Appendix 1)
Summary
58 The Open Dentistry Journal, 2021, Volume 15 the method of choice to evaluate bone [10 - 12]. Despite the limitations related to the technique, a recent study reported an acceptable accuracy for the assessment of trabecular bone. It is expected that high-resolution parameters may provide higher accuracy for bone assessment. Due to the capability of the technique of providing images with a spatial resolution up to 2 μm, microcomputed tomography (μCT) is considered the gold-standard technique to evaluate jaw bone in laboratory research works. This study proposed to compare the trabecular bone assessment by two CBCT devices in regard to the μCT. The null hypothesis is that there is no difference in trabecular bone parameters acquired from μCT and CBCT devices. Cone-Beam Computed Tomography (CBCT) with high-resolution parameters may provide an acceptable resolution for bone assessment
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