Assessment of the variability of the hematological and biochemical parameters in giardiasis patients

Abstract

Giardiasis is one of the essential parasitic intestinal diseases, widespread in many countries. Therefore, it has occupied a necessary place among public health priorities. Children are the most vulnerable and affected by this disease. The current study evaluated the physiological and biochemical hematological changes of affected children under 12 in Al-Diwaniyah Governorate, middle of Iraq. Hemoglobin levels and the volume of compacted blood cells decreased in patients (10.4g/dL and 33.7%, respectively). In contrast, the number of white blood cells increased to (7700 cells/mm3), indicating substantial differences between the hematological parameters and the control group's results. Regarding the number of cells, the investigation revealed a reduction of (64.1%) in the total number of cells. In contrast to the control data, the results showed a rise in the number of lymphocytes, eosinophils, and basophils, with respective percentages of (%28.4), (%0.6), and (%0.4). Monocytes were unaffected. The findings of the biochemical parameters demonstrated that the concentrations of liver enzymes varied significantly, with the attention of GPT and GOT increasing to(18.7) and (19.9)international units/liter. Additionally, lipid level variations, including lower cholesterol and triglycerides, were discovered. Compared to the control groups, it reached (163.8) and (122.5) mg/DL. Keywords: Giardiasis, blood parameters, GOT, Giardia lamblia.