Abstract
BackgroundPost stroke delirium is a multifactorial life-threatening process, still poorly understood. The aim of the study was to identify the risk factors associated with the development of delirium in acute stroke patients and detection of the effect of delirium on the short-term prognosis of acute stroke patients.Patients and methodsThis study was carried on 74 acute stroke patients, 40 males (54.1%) and 34 females (45.9%). Full general and neurological examination was performed to all patients. Full routine laboratory investigation and computed tomography scan and/or magnetic resonance imaging of the brain were done.ResultsThe patients were divided into two groups: 15 patients with delirium (group I) and 59 patients without delirium (group II). The incidence of delirium was higher among patients with older age (P = 0.002). There was no statistically significant relationship between incidence of delirium and sex of patients (P = 0.52). The delirium patients had significantly higher National Institutes of Health Stroke Scale (NIHSS) (P = 0.001) and lower Glasgow Coma Scale (GSC) (P = 0.001) at admission. They also had high mortality (P = 0.017) and lower Barthel Index (BI), and these results were statistically (P = 0.001) significantly.ConclusionPost stroke delirium was associated with old age, higher NIHSS at admission, intracerebral hemorrhage, and higher long-term mortality.
Highlights
The term stroke encompasses a wide diversity of vascular diseases of the central nervous system
Post stroke delirium was associated with old age, higher National Institutes of Health Stroke Scale (NIHSS) at admission, intracerebral hemorrhage, and higher long-term mortality
A value of P < 0.05 was considered statistically significant. This cohort study was conducted on 74 stroke patients (40 male, 54.1%; 34 female 45.9%) who were admitted in Intensive Care and Stroke Units, Neurology Department, Zagazig University
Summary
The term stroke encompasses a wide diversity of vascular diseases of the central nervous system. Stroke is considered the second most common cause of death and the seventh leading cause of disability worldwide [1]. Delirium is defined by the American Psychiatric Association as an acute, transient disorder of cognition and consciousness with fluctuating intensity [2]. If delirium is not detected on admission to a hospital, the risk of death may be increased eightfold [4]. Post stroke delirium is a multifactorial life-threatening process, still poorly understood. The aim of the study was to identify the risk factors associated with the development of delirium in acute stroke patients and detection of the effect of delirium on the short-term prognosis of acute stroke patients
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