Abstract
The present study deals with the development of scaffolds based on gelatin (G) and/or chitosan (CH) through modifications in the central processing method. This process consists of the fabrication of a hydrogel which is, then submitted to a freeze-drying stage. To compare the effects of the different modifications, the mechanical properties of the various systems were characterized, employing both dynamic compressive strain and frequency sweep tests. In addition, their porosity as well as the structure and fiber distribution, using an analytic model and scanning electron microscopy (SEM), were also evaluated. The obtained results demonstrated a strong dependence on the properties by the scaffolds with both the modifications introduced in the processing method as well as the proportion of materials used (G and CH). Furthermore, the properties were found to improve for systems with a high chitosan content after being submitted to a heat treatment at 50 °C with agitation.
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