Abstract
Objective: Novel COVID-19 virus is extensively being studied for its long-term effects. A predominant trend of development of Diabetes Mellitus (DM) in Covid-19 patients is being observed, and hence further relation is explored in this study. Methods: This is an observational inductive retrospective study conducted for four months in a tertiary care hospital. The study included subjects who recovered from COVID-19 and were treated post-COVID-19 in the hospital. The subjects who had stable glucose counts were excluded. The data obtained from the medical record department encompassed demographic details and clinical data of the patient. The data were tabulated, and observations were reported using descriptive analysis. Results: Among 5632 admitted patients for COVID-19, 694 came for follow-up. 105 patients were re-admitted, but 11 had newly developed DM, and 14 observed uncontrolled DM managed by medical attention. The reported incidence rate in Newly-Diagnosed DM was 0.195%, and the person above 41 y was at greater risk. Similarly, the incidence rate in Uncontrolled-DM was 13.33%, and persons above 47 y were at greater risk. It was found that both these categories of patients had comorbidities, and the development of this was seen between the 25th-40th day. In both cases, males were more prone than females. Conclusion: The study reports a bi-directional relationship between Covid-19 and DM. The use of steroids may have stepped-up this relationship. Cautious use of steroids, changes in the hospital formulary, and further quantitative clinical investigations are primary recommendations that may prevent such episodes.
Highlights
Covid-19, being a relatively recent virus, has much scope and research for analysis
The present study was aimed to find out the incidence of diabetes mellitus in COVID-19 patients after the infection and its possible causes
A total of 5632 COVID-19 patients were admitted and treated for COVID-19 until the end of April 2021, and the records showed 694 patients came for follow-up, of which 105 patients were re-admitted for some complications till March 2021
Summary
Covid-19, being a relatively recent virus, has much scope and research for analysis. Evidence regarding COVID-19 has yet been emerging, and current information has given researchers the latest perspective regarding it. Such is observed as a relationship between Covid-19 and Diabetes Mellitus. Individuals with Diabetes Mellitus, Hypertension, and severe Obesity (BMI less than 40 kg/m2) are more likely to be infected. They are at higher risk for complications and death from COVID-19 [4]. Between COVID-19 and Diabetes, there is a bidirectional/relationship [6]. Diabetes is linked to a higher risk of extreme COVID-19. In patients with Covid, new-onset diabetes and serious metabolic complications of pre-existing diabetes, such as diabetic ketoacidosis and hyperosmolarity, necessitating extremely high insulin doses, have been observed [7,8,9]
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More From: International Journal of Pharmacy and Pharmaceutical Sciences
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