Abstract
Methods The protocol was performed in 3 healthy volunteers. All imaging was performed on a 3 T whole-body-scanner (Achieva, Philips Medical Systems, Netherlands) with a segmented gradient echo phase contrast black blood imaging sequence. 6 long axis views were acquired at 30° angular spacing. The imaging parameters were: TR/TE = 6.8 ms/4.6 ms, resolution 2 × 2 × 8 mm3, flip angle 15°, VENC = 15 cm/s in through plane direction, 30 heart phases. Black-blood contrast was achieved by the application of two alternating saturation-prepulses with 5 mm distance to the imaged slice. Image acquisition time for each slice was 1:04 minutes. Quantitative through-plane motion analysis was performed by an in-house developed analysis software. After manual segmentation of the left ventricle the rotation angle φ was calculated for apical, equatorial and basal segments and compared for retrieval of the twisting motion component. Results Figure 1 shows the anatomical (a) and c)) and velocity encoded (b) and d)) images exemplarily for one of the 6 long axis views of one volunteer. The opposing rotational direction of the apex and the basis is clearly revealed in both images. Figure 1e) displays the resulting rotation curves for the myocardial lateral wall. The twist angle (curve blue) shows the typical systolic twisting and diastolic untwisting. The twist angle was the minimal in the septal wall as also described in [3].
Highlights
Several studies have revealed the relevance of assessing the rotational motion of the heart, especially for selection of DCM patient for CRT therapy, in which a reduced LV twisting was found to be predictive for the response [1,2]
The purpose was to evaluate the possibility of combining conventional CINE imaging techniques in long axes geometry with through-plane velocity-encoding for fast simultaneous assessment of the twisting motion
All imaging was performed on a 3 T whole-body-scanner (Achieva, Philips Medical Systems, Netherlands) with a segmented gradient echo phase contrast black blood imaging sequence. 6 long axis views were acquired at 30° angular spacing
Summary
Several studies have revealed the relevance of assessing the rotational motion of the heart, especially for selection of DCM patient for CRT therapy, in which a reduced LV twisting was found to be predictive for the response [1,2]. The purpose was to evaluate the possibility of combining conventional CINE imaging techniques in long axes geometry with through-plane velocity-encoding for fast simultaneous assessment of the twisting motion
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