Abstract
Background One of the most important tasks in the treatment of atopic dermatitis (AD) is alleviation of racking skin dryness and persistent pruritus, because these factors exert a significant influence on worsening patients' quality of life. Cryotherapy being a new form of rehabilitation in AD may supplement and support a long-term process of AD treatment, because it has anti-inflammatory and antipruritic effects and exerts a positive influence on the nervous system. Methods 14 adults (mean age 32 ± 10.8) with mild to moderate AD were enrolled. WBC (15 treatments in total) took place in winter 2018/2019. Patient skin parameters (hydration of the epidermis, sebum level, and skin pH level) were measured with probes produced by Courage + Khazaka Electronic GmbH. Results Changes were observed in the hydration level of the epidermis. The SCORAD index evaluating the AD intensity level also changed (decreased). Conclusion Due to these properties, hypothesis has been put forward that WBC can be an effective, supporting method in the treatment of AD.
Highlights
A number of factors exert an influence on proper functioning of the skin barrier
The following inclusion criteria were used in the study: age above 18 years, no contraindications to Whole-body cryotherapy (WBC) procedures, and clinically diagnosed with atopic dermatitis (AD)
Of the patients who left the study, 2 patients discontinued owing to worsening dermatitis and the other 4 for reasons not related to skin condition
Summary
A number of factors exert an influence on proper functioning of the skin barrier. These include the level of hydration and skin pH, quantity and composition of intracellular lipids, corneocyte cellular properties, and their cohesion in the cornified layer. Dry skin in atopic patients is associated with abnormal activity of the hydrolipid barrier. One of the most important tasks in the treatment of atopic dermatitis (AD) is alleviation of racking skin dryness and persistent pruritus, because these factors exert a significant influence on worsening patients’ quality of life. Due to these properties, hypothesis has been put forward that WBC can be an effective, supporting method in the treatment of AD
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