Abstract
Introduction: Pregnancy presents uncommon issues regarding anti-infection treatment. A significant concern is the conceivable teratogenic or harmful impact on the fetus.
 Objectives: The objectives of this study are to assess the infections and use of antibiotics in pregnancy among the pregnant women reported at Gynae OPD Civil Hospital Khairpur Mirs Pakistan.
 Methodology: This was an observational cross-section study conducted at Gynae OPD Civil Hospital Khairpur Mirs Pakistan from July 2020 to January 2021. A total of 400 sample size was calculated by using Slovin’s Formula. Data were collected by purposive sampling technique. Finally, collected data were analyzed by using a statistical package for social science (SPSS) software version 24. 
 Results: Results reported commonly prescribed antibiotics during the pregnancy in which Phenoxymethylpenicillin was most commonly prescribed i.e. 31% and it was indicated for Maxillary sinusitis 40% and Acute tonsillitis 74%. The infections which were diagnosed during pregnancy among which vaginal candidiasis was high 117 (29.2%). Common antibiotics duration of treatment was observed in which penicillin frequency for 8-10 days was high 39 (9.7%). Common prescribed antibiotic dosages during pregnancy were observed in which the frequency of penicillin's recommended dose was high at 80 (20%). Antibiotics timing during pregnancy was observed in which Metronidazole+Tinidazole were mostly used during II trimester.
 Conclusion: The antibiotics use in Khairpur Mirs is very high. The dosage regiment should be properly monitored, according to the pharmacokinetic data of particular antibiotics during the pregnancy.
Highlights
Pregnancy presents uncommon issues regarding anti-infection treatment
The infections which were diagnosed during pregnancy among which vaginal candidiasis was high 117 (29.2%)
Common antibiotics duration of treatment was observed in which penicillin frequency for 8-10 days was high 39 (9.7%)
Summary
Objectives: The objectives of this study are to assess the infections and use of antibiotics in pregnancy among the pregnant women reported at Gynae OPD Civil Hospital Khairpur Mirs Pakistan. A significant concern is the conceivable teratogenic or harmful impact on the fetus. Again, the danger of treating with dosages of sub-therapeutic or less effective drugs when attempting to secure the fetus, ought to be dodged. Doctors have been hesitant to endorse antibiotics for pregnant ladies because a couple of antimicrobials were on the rundown of human teratogens (e.g., tetracyclines), others have been teratogenic in experiments of animal (e.g., gentamycin), a couple may have a poisonous or toxic impact postnatally (e.g., streptomycin) [2]
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