Assessment of the infarct size with ST-elevation from high-resolution standard and orthogonal ECG leads

Abstract

The high-resolution electrocardiography is known to be a useful tool for extraction and analysis of low-amplitude signal components. We found the high-resolution standard and synthesized orthogonal electrocardiography leads may be useful for precise evaluation of the zone of acute myocardial infarct necrosis. We found high-resolution electrocardiography may be useful for precise location of the site of the myocardial necrosis and assessment of the severity of impaired left-ventricle systolic function of patients with ST-elevation myocardial infarct (STEMI) in the acute phase. High-resolution (1 MHz) ECG from 4 groups were collected: healthy controls (13), patients with anterior (10), inferior STEMI (19) and 12 patients with infero-lateral AMI). The three orthogonal leads X, Y, Z were synthesized from the 12-standard leads by known transformation. The possibility for facilitated and fast performance of this examination in clinical conditions, including emergency, the lack of necessity of specially trained staff for carrying out the examination and interpretation of the results, as well as the very low prime cost, make this electrophysiological method very suitable for application in the routine clinical practice for qualitative and quantitative assessment of patients with acute coronary syndromes.