Assessment of the health status of infants born from women of the late reproductive period

Abstract

Objective.To assess the condition of newborns from women of the late reproductive period (LRP), depending on the parity of births.Material and methods.The authors examined 130 pregnant women and their 130 newborns. Group I consisted of 60 primiparouswomen of late reproductive period and their 60 newborns, Group II included 40 multiparous women of the late reproductive periodand their 40 newborns, Group III (control group) consisted of 30 healthy pregnant women aged from 18 to 25 years and their 30newborns. The authors performed a retrospective analysis of the gestation course and perinatal outcomes. Ultrasound and neurosonography were used among the instrumental research methods.Results.Women of the late reproductive period gave birth to children in a state of asphyxia twice more often, who develop neurologicaldisorders 1,5 times more often and complex postnatal adaptation and disorders of the perinatal period are twice more likely. Amongwomen of the late reproductive period, primiparous women gave birth to children with the most severe disorders.Conclusion.The high incidence of neurological diseases in children born from women of the late reproductive period is associatedwith age-related changes in their germ cells, the implementation of assisted reproductive technologies, and the intake of hormonaldrugs in early pregnancy. The data obtained should be taken into account by obstetricians in the course of pregnancy in women of latereproductive age; they should be included in the group of high risk of developing neurological disorders in children.