Abstract
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is still a severe threaft for human health currently, and the researches about it is a focus topic worldwide.
 Aim of the study: In this study, we will collect some laboratory results of the patients with coronavirus disease (COVID-19) to assess the function of liver, heart, kidney and even pancreas. 
 Subjects and Methods: Laboratory results of the patients with COVID-19 are collected. The biochemical indices are classified and used to assess the according function of liver, heart, kidney; meantime, and blood glucose is also observed and taken as an index to roughly evaluate pancreas.
 Results: There were some indices exhibited abnormal. For patient 1, the ratio of albumin and globulin slightly was lower than the down-limit of reference range. For patient 2, alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), creatine kinase (CK), creatinine kinase-MB isoenzyme (CK-MB), lactate dehydrogenase (LDH), alpha-hydroxybutyric dehydrogenase (HBDH), and beta-2 microglobulin (β2-MG) were respectively higher than the according upper limit of the reference range, while prealbumin (PA) was lower than the down limit. For patient 3, GGT, CK, PA were high than normal range. For patient 4, CK, LDH, HBDH were higher than the upper range.
 Conclusion: Infection of SARS-Cov-2 could cause liver and heart injury, and it is suggested that clinicians and researchers should pay more attention on the prevention, treatment and causative mechanism of such an injury.
Highlights
Clinical and pathological features of patients with COVID-19 have recently been reported, which showing that SARS-Cov-2 infection causes clusters of severe and even fatal pneumonia.[3,7] The common symptoms of this pneumonia includes fever, fatigue, and dry cough, followed always by anorexia, myalgia, dyspnea, and so on.[2,8] Presently, except for lung injury caused by SARS-Cov-2, some researchers found that the new coronavirus affected other multiple organs, especially including the three most important ones: hear,(9) kidney[10] and liver[11]
ALB versus GLO (A/G), GGT, lactate dehydrogenase (LDH) and hydroxybutyric dehydrogenase (HBDH) followed with the similar ratio of 50%
The key disease caused by SARS-Cov-2 was pneumonia, and the patients generally exhibited respiratory symptoms including fever, cough, diarrhea, sore throat, dyspnea, and so on.[8,12] Along with more and deeper researches, scholars found that beside lung the, other organs or tissues were injured in the course of COVID-19, such as heart, liver, kidney, and even the immune system.[3,13,14] What is more serious that part of the patients with COVID-19 died due to the multiple organ failure, shock, acute respiratory distress syndrome, heart failure, arrhythmias, or renal failure.[14,15] beside pneumonia, the status of other organs should be paid more attention in the progress of diagnosing and treating COVID-19
Summary
Clinical and pathological features of patients with COVID-19 have recently been reported, which showing that SARS-Cov-2 infection causes clusters of severe and even fatal pneumonia.[3,7] The common symptoms of this pneumonia includes fever, fatigue, and dry cough, followed always by anorexia, myalgia, dyspnea, and so on.[2,8] Presently, except for lung injury caused by SARS-Cov-2, some researchers found that the new coronavirus affected other multiple organs, especially including the three most important ones: hear,(9) kidney[10] and liver[11] These findings are not extracted from surgery or autopsy but laboratory tests. Aim of the study: In this study, we will collect some laboratory results of the patients with coronavirus disease (COVID-19) to assess the function of liver, heart, kidney and even pancreas
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