Abstract
The effects of the low dialysate flow rates on the removal rate and clearance of urea nitrogen, creatinine, uric acid, beta 2-microglobulin and myoglobin, using high flux membranes were studied. The removal rates for all substances were not significantly decreased. Although clearance of urea nitrogen, creatinine and uric acid was significantly decreased (p < 0.05), clearance of inorganic phosphate, beta 2-microglobulin and myoglobin was not significantly decreased. These results suggest that hemodialysis at low dialysate flow rates for a short term during water shortages due to natural disasters and drier climates can be performed with an insignificant reduction in removal rates and a minimum reduction in clearance.
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