Abstract
Background: A serious worldwide medical and public health concern occurs with the dengue virus, which is also an emerging health threat. A victim can be vulnerable and acquire dengue because of his age, genetics, nutritional status, viral strain and secondary infections. Our objective was to identify the ABO blood group system's distribution and relationship in dengue fever (DF) patients.
 Methodology: The current study has conducted between September 2019 and September 2020 in Dr. Ishrat ul Ebad Institute of Blood Diseases Department. The research work was viewed and accepted by the ethics and research committees. Case records of patients with blood systems and their relation among dengue nonstructural protein 1 (NS1) antigen /dengue immunoglobulin M (IgM) and immunoglobulin G (lgG) were included in this study.
 Results: Among 204 cases, 82 were blood group O positive, 59 were B positive, 38 were A positive, 16 were AB positive, 4 were O negative, and 2 were blood group A negative. The association of the ABO blood group with dengue was statistically significant (p=0.046). Blood group O+ has the highest number of cases, 66 (42.9 %), than controls, 16 (32 %).
 Conclusion: This study overall consummates that blood group O is linked with a greater possibility of acquiring DF in comparison with different other blood group types. There is a significant relationship between blood group and DF observed.
Highlights
A serious worldwide medical and public health concern occurring is with dengue virus, which is an emerging health threat[1]
The results of the present study suggest that there is an association of dengue fever (DF) with blood groups
This study consummates that blood group O is linked with a greater risk of acquiring DF than those with different blood groups
Summary
A serious worldwide medical and public health concern occurring is with dengue virus, which is an emerging health threat[1]. Aedes mosquitoes is the culprit to transmit this arboviral infection having “DENV -1,” “-2,” “-3,” and “-4,” strands[2] These hands can cause varied effects, including being asymptomatic to diverse effects of consistent fever, DF, dengue-shock syndrome (DSS) and dengue hemorrhagic fever (DHF). After clinical signs manifest from the first to the fifth day, NS1 antigen, a glycoprotein, can be seen. It can either be detected by immune-enzymatic technique or immune-chromatographic[7,8]. Case records of patients with blood systems and their relation among dengue nonstructural protein 1 (NS1) antigen /dengue immunoglobulin M (IgM) and immunoglobulin G (lgG) were included in this study. There is a significant relationship between blood group and DF observed
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