Abstract
The tomato (<i>Lycopersiconesculentum</i> Mill) is a herbaceous plant of the Solanaceae family widely cultivated for its fruit. It is one of the most consumed fruits in the world because of its nutritional potential. Indeed, tomato is rich in secondary metabolites and compounds with antioxidant power known for their beneficial effects on health. This study aims to evaluate the antihypertensive and antihyperhocysteinemic activity of two varieties of tomatoes grown in Côte d'Ivoire, namely <i>Locale côtelette</i> and <i>Cobra F1</i>. To do this, rats made hypertensive and hyperhomocysteinemic were treated at a dose of 50 and 100 mg/kg bw for 8 days with the extracts of these tomatoes. At the end of this treatment, the results indicate a decrease in the serum level of LDL-cholesterol and creatinemia respectively of 79.92% and 18.82% in comparison with those of hypertensive rats which did not undergo any treatment. In addition, serum homocysteine level decreased by 35% compared with untreated hyperhomocysteinemic rats. Moreover, a 13.33% increase in serum HDL-cholesterol was observed. In view of the results obtained, regular consumption of tomatoes could help fight against high blood pressure, atherosclerosis, renal failure and prevent cardiovascular complications such as thromboembolic diseases.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
