Abstract
BackgroundTo investigate the diagnostic value of dual-source computed tomography (DSCT) in the evaluation of tetralogy of Fallot (TOF)-associated extracardiac vascular abnormalities in pediatric patients compared with transthoracic echocardiography (TTE).MethodsOne hundred and twenty-three pediatric patients diagnosed with TOF were included in this retrospective study. All patients underwent DSCT and TTE preoperatively. All associated extracardiac vascular abnormalities and their percentages were recorded. The diagnostic performances of DSCT and TTE were compared based on the surgical results. The image quality of DSCT was rated, and the effective radiation dose (ED) was calculated.ResultsA total of 159 associated extracardiac vascular deformities were confirmed by surgery. Patent ductus arteriosus (36, 22.64%), right-sided aortic arch (29, 18.24%), and pulmonary valve stenosis (23, 14.47%) were the most common associated extracardiac vascular abnormalities. DSCT was superior to TTE in demonstrating associated extracardiac anomalies (diagnostic accuracy: 99.13% vs. 97.39%; sensitivity: 92.45% vs. 77.07%; specificity: 99.81% vs. 99.42%). The agreement on grading the image quality of DSCT was excellent (κ = 0.80), and the mean score of the image quality was 3.39 ± 0.50. The mean ED of DSCT was 0.86 ± 0.47 mSv.ConclusionsCompared to TTE, low-dose DSCT has high diagnostic accuracy in the depiction of associated extracardiac vascular anomalies in pediatric patients with TOF, and could provide more morphological details for surgeons.
Highlights
To investigate the diagnostic value of dual-source computed tomography (DSCT) in the evaluation of tetralogy of Fallot (TOF)-associated extracardiac vascular abnormalities in pediatric patients compared with transthoracic echocardiography (TTE)
Hu et al BMC Cardiovascular Disorders (2017) 17:285 study, we enrolled 123 pediatric patients to investigate the diagnostic performance of DSCT compared with that of transthoracic echocardiography (TTE) for assessing associated extracardiac vascular abnormalities in pediatric patients with TOF
The most common symptoms in the pediatric patients referred to our hospital were heart murmurs (79/ 123, 64.23%), cyanosis (30/123, 24.39%), and post-exercise tachypnea (5/123, 4.07%) (Table 1)
Summary
To investigate the diagnostic value of dual-source computed tomography (DSCT) in the evaluation of tetralogy of Fallot (TOF)-associated extracardiac vascular abnormalities in pediatric patients compared with transthoracic echocardiography (TTE). Dual-source computed tomography (DSCT) has become regarded as a reliable non-invasive tool for delineating various anomalies in pediatric patients with complex CHD [3,4,5, 8,9,10,11]. To the best of our knowledge, few studies have focused on the preoperative evaluation of associated extracardiac vascular anomalies in pediatric patients with TOF using DSCT, especially not large case series studies. Hu et al BMC Cardiovascular Disorders (2017) 17:285 study, we enrolled 123 pediatric patients to investigate the diagnostic performance of DSCT compared with that of transthoracic echocardiography (TTE) for assessing associated extracardiac vascular abnormalities in pediatric patients with TOF
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