Abstract

An impaired internal circadian clock or misalignment with the 24-h environment disruption can greatly impact cognitive function and attention, mood, and addictive behavior. Disrupted sleep or sleep timing is associated with poor outcomes in neuropsychiatric disease, impacting symptoms over the course of the 24-hour day. Surprisingly, few studies have examined these temporal patterns of symptoms (such as withdrawal and craving in the case of addiction or attention in the case of ADHD). In this symposium presentation, we will discuss the impact of chronotype and dysregulated circadian timing on neuropsychiatric disease such as addiction (e.g., smoking) and attention deficit disorders.

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