Assessment of some indicators of oral liquid in children with the pathology of the temior-lower under jaw joint

Abstract

The problem of the relationship between dental and somatic health in children and adolescents is of interest to researchers and does not lose relevance. Firstly, this is due to a tendency to increase the frequency of somatic and dental diseases in children. Secondly, this is due to the fact that modern concepts of the development of diseases, new clinical forms of pathologies arise, research methods, diagnostics and treatment are improved. During the interaction of lysozyme with a substrate of Micrococcus lysodeikticus, substrate bleaching is observed, which is recorded spectrophotometrically. The degree of enlightenment is proportional to the activity of lysozyme, which was expressed in units/ml of oral fluid [Levitsky AP, 2005]. Catalase activity in the oral fluid was evaluated using a method based on the ability of hydrogen peroxide, which did not react with catalase, to combine with molybdenum salts into a stable orange complex. Thus, in children with TMJ disease, imbalances in the prooxidant-antioxidant system are observed; a decrease in catalase activity and an increase in the level of malondialdehyde, a decrease in antimicrobial protection and an increase in the degree of contamination of pathogenic and conditionally pathogenic microflora. In children with TMJ pathology, a significant decrease in the lysozyme content in the oral fluid and a simultaneous increase in urease activity relative to these healthy children were recorded. This suggests that in children with TMJ, there was a decrease in the level of antibacterial protection of the oral fluid, as a result of which the degree of contamination of the oral cavity with pathogenic and conditionally pathogenic microflora increased.