Assessment of serum vitamin D level in women with polycystic ovary syndrome

Abstract

Back ground: PCOS is the commonest endocrinopathy among women of reproductive age. Its worldwide prevalence has been estimated between5-10%. Rotterdam criteria is known to be the most important in such patients.Vitamin D, a fat-soluble vitamin, can be produced in two ways: by intestinal absorption and endogenous synthesis from a precursor of 17-hydroxyl cholesterol on the skin with sufficient exposure to ultraviolet sunlight. Most references consider a serum 25(OH) vitamin D of < 20 ng/ml as vitamin D deficiency. Aim of the work: The aim of this work is assessment of the level of vitamin D in female have polycystic ovary syndrome & healthy female. Patient and methods: This is a case control study held in Misr Al-Gadeda Military Hospital in gynecology outpatient clinic from May 2020 - May 2021.Patients selected from attendees of the outpatient gynecological clinic and inpatient gynecological ward at Misr Al-Gadeda Military Hospital. Group A: 45 women diagnosed with PCO based on Rotterdam Criteria 2003. Group B: 45 fertile women without PCOS . Results: The results indicated that 25(OH) vitamin D was significantly lower in PCOS group than in control group. There were no significant correlations between 25(OH) vitamin D and age and BMI. Conclusion: PCOS is known to be one of the commonest endocrine problems between female of the reproductive age.25 (OH) Vitamin-D was significantly lower in PCOS group than in the control group.No significant difference was found in Vitamin D level related to age group and body mass index.