Abstract
Background: Data from experimental tumor models suggest that mast cells accumulate near tumor cells before the onset of angiogenesis and that they are required for the macroscopic expansion and metastatic spread of primary tumor cells. Tryptase, a serin protease stored in mast cell granules, plays a role in tumor angiogenesis. Mast cells can release tryptase following c-Kit receptor activation. The aim of this study was to assess serum tryptase levels in colorectal cancer patients before and after radical resection and to quantify c-Kit expressing cells in primary tumor tissue.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
