Abstract
Introduction: Sepsis constitutes one of the most prevalent cause of mortality in newborns, eminently in developing countries. There are several investigations available that may be used as indicators to identify sepsis, however, the inability of a single laboratory investigation for rapid detection and diagnosis of sepsis, calls for the need of a specific investigation. Lately, it has been proclaimed that procalcitonin can be used as a reliable predictor for diagnosis and to determine severity as well as outcome of neonatal sepsis. Objective: To assess levels of serum Procalcitonin level as a marker to diagnose late-onset sepsis in a neonatal intensive care unit (NICU). Methods and Materials: A cross-sectional study was performed between the June 2018 to November 2018 at Sree Balaji Medical College and Hospital. Serum procalcitonin levels were determined for 25 neonates of age between 3-30 days. Results: Distinct elevations of procalcitonin levels were observed in neonates with late-onset sepsis caused mainly by coagulase-negative staphylococci. Currently nosocomial infection due to coagulase-negative staphylococci is a frequent occurrence in NICUs. Conclusion: Serum procalcitonin is an efficient tool to diagnose Late Onset of Sepsis.
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