Abstract
Background: Role of IL-4 and Ig-E in aetiopathogenesis of pityriasis alba (PA) is questionable. Aim: To assess the serum IL-4 and Ig-E levels in pityriasis alba patients. Patients & Methods: Thirty patients with pityriasis alba (group I) (n=30) and thirty volunteers (group II) completed the study (n=30). IL-4 and Ig-E were measured in patients’ sera with enzyme linked immune sorbent assay (ELISA). Results: There was statistically significant correlation between IL-4 and PA which points to the role of Th2 and IL-4 in pathogenesis of PA. There was no statistically significance between Ig-E and either PA or IL-4 level. Conclusion: Imbalance of IL-4 level may play a critical role in pathogenesis of PA. Changed balance of IL-4 level may be related to the genetic background of patients, and adds more evidence to the association of PA and atopic dermatitis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
