Abstract
Background: Altered lipid levels may occur in ischemic stroke, as well as stroke-related diseases like hypertension, diabetes and coronary heart diseases. The purpose of this study was to evaluate the reliability and accuracy of lipid profile assessment in saliva of patients with ischemic stroke and patients with some stroke-related diseases. Patients & Method: This study was conducted on total of 150 individual to assess salivary and serum total cholesterol (TC), triglycerides (TG), high density lipoproteincholesterol (HDL-C), low density lipoproteincholesterol (LDL-C) and very low density lipoprotein (VLDL-C) .They are divided into three group. The first group consists of fifty patients with recently diagnosed ischemic stroke (based on brain CT), the second group (risk group) consists of seventy five patients grouped into 3subgroups; 25 patients with hypertension, 25 patients with type 2 diabetes mellitus and other 25 patients with coronary heart disease. The last group (control group) consists of 25 individuals who are clinically healthy. Results: Salivary TC, TG, LDL-C and VLDL-C concentrations were significantly high in patients with ischemic stroke when compared with risk and control groups. On the other hand, only serum TG, HDL-C and VLDL-C concentrations showed significant elevation (p 0.5). Conclusion: Lipid profile can be assessed in saliva and can be used as simple, monitoring tool in stroke-prone individuals with reasonable accuracy.
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