Abstract
Objective: To observe the relationship of deep-slow respiratory pattern and respiratory impedance(RI) in patients with chronic obstructive pulmonary disease (COPD).Methods: RI under normal respiration and during deep-slow respiration was measured one after the other with impulse oscillometry for 8 patients with COPD and for 9 healthy volunteers as control.Results: When respiration was changed from normal pattern to the deep-slow pattern, the tidal volume increased and respiratory frequency significantly decreased in both groups (P < 0. 01), the total respiratory impedance (Z respir) showed a decreasing trend in COPD group, but with no obvious change in the control group. No change in the resonant frequency (fres) was found in both groups, and the respiratory viscous resistance obviously decreased in the COPD group(R5: P=0.0168; R20: P=0.0498; R5-R20: P=0.0388), though in the control group it was unchanged.Conclusion: IOS detection could reflect the response heterogeneity of different compartments of respiratory system during tidal breathing. During deep-slow respiration, the viscous resistance in both central airway and peripheral airway was decreased in patients with COPD. RI measurement by impulse oscillometry may be a convenient pathophysiological method for studying the application of breathing exercise in patients with COPD.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
