ASSESSMENT OF RELATIONSHIP BETWEEN NEUROLOGICAL MANIFESTATIONS AND INFLAMMATORY MARKERS IN COVID-19 PATIENTS IN TERTIARY CARE HOSPITAL.

Abstract

acute respiratory syndrome coronavirus 2, has resulted in more than 5.9 billion conrmed cases worldwide and more than 6.4 million deaths. Although the most common and important presentation is with respiratory disease, reports of neurological features are increasing. Characteristic cytokine storm incites severe metabolic changes and multiple organ failure. Profound coagulopathies may manifest with ischemic or hemorrhagic stroke. A prospective observational study was conducted in tertiary care government hospital in Kakinada for a period of 2months (April 1st, 2021 – May 31st, 2021). A total of 50 patients were participated in this study. Thorough clinical examination and relevant Lab, Radiological investigations were performed. Descriptive analysis of collected data was done. Mean age of the patients (SD) was 62.57(3.48). Majority of the patients were above 60years of age. 24(48%) were males and 26(52%) were females. Most common symptom was headache (60%), followed by focal neurological decit (38%). 33(66%) of patients have Co-morbidities. 3(6%) patients were Vaccinated for Covid. There was a signicant difference observed between inammatory markers and Covid patients with respect to neurological manifestations. Out of 50 patients 11(22%) were succumbed while 39(78%) were survived