Year-end Sale % OFF 
Abstract
Context: The clinical importance of evaluating skeletal maturation has long been recognized by the health professions. Skeletal maturation is an integral part of individual patterns of growth and development.With many orthodontic patients, pubertal growth needs to be factored into the diagnostic equation.Accurate prediction of the timing of the pubertal growth spurt and the amount of remaining growth affects the treatment decisions in orthodontics, orthognathic surgery and dental implantology.IGF-1 mirrors growth hormone levels. Thus, IGF-I might be a good indicator of residual mandibular growth. Aims: To establish a relationship between IGF-1 levels evaluated from blood samples and MP3 stages of skeletal maturity. To investigate the relationship between the IGF-1 and the skeletal age. Methods and Material: The sample size consisted of 40 subjects between the age group of 5 – 25 including both the sexes. The periapical radiographs for MP3 and blood sample for IGF-1 was collected. Sample was sent to the lab to determine IGF-1 values. Statistical analysis used: Descriptives, ONE way ANOVA, POST HOC test, Spearman coefficient. Results: Results showed that IGF-1 levels at the peak pubertal growth were statistically higher than the start of pubertal growth, acceleration, deceleration, maturation of growth spurt and on completion of growth. There was statistically significant positive correlation between IGF-1 and MP3 stages. Conclusions: From the present study it can be concluded that IGF-1 can be successfully used as a skeletal maturity indicator. Key-words: IGF-1, MP3, GH Key Messages:The results of this study shows that mean IGF-I levels at pubertal and post pubertal stages were significantly higher than at the other stages. From the present study it can be concluded that IGF-1 can be successfully used as a skeletal
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
