Abstract

Assessment of Quality of Life and Severity of Itching Pre and Post Doxepin Therapy in Dialysis Patients with Pruritus

Highlights

  • Pruritus is common in patients with Chronic Kidney Disease (CKD) stages 4 and 5

  • Clinicians should enquire about skin irritation and itching during consultations since patients may be reluctant to admit to these symptoms due to embarrassment

  • Pruritus is a common and bothersome symptom among patients with endstage-renal-disease (ESRD) (Nolan, 2005).Chronic kidney disease (CKD)-associated pruritus is a significant clinical symptom affecting more than 50% of patients on hemodialysis (Mettang and Weisshaar, 2010)

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Summary

Introduction

Pruritus (skin irritation or itching) is common in patients with Chronic Kidney Disease (CKD) stages 4 and 5. It is associated with disrupted sleep, reduced quality of life, depression and increased mortality (Rayner et al, 2012). Pruritus is a common and bothersome symptom among patients with endstage-renal-disease (ESRD) (Nolan, 2005).Chronic kidney disease (CKD)-associated pruritus is a significant clinical symptom affecting more than 50% of patients on hemodialysis (Mettang and Weisshaar, 2010). People with end-stage kidney disease have a higher incidence of skin itching than the general population, while dialysis raises this high incidence. Dr Kousalya Prabahar, Assistant Professor, Department of Pharmacy. Faculty of Pharmacy, University of Tabuk, Tabuk, Kingdom of.

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