Abstract
Polycystic ovary syndrome (PCOS) is one of the most problematic neuroendocrine syndromes in gynecology. It affects 6–25 % of reproductive-age women. Aim of research. To assess the quality of life in women with PCOS in early and active reproductive age. Materials and methods. The basic group consisted of 90 women with PCOS and was divided into the I and II subgroups. 60 women aged 18–25 years formed the I subgroup, 30 patients aged 26–35 years – the II one. 30 women without this pathology were controls. Diagnosis of PCOS was based on theRotterdam criteria. Quality of life was assessed with the help of the 36-Item Short Form Health Survey. Results. The parameters of quality of life physical component in women of the basic group were slightly less than in controls. Statistically significant difference was determined only in persons of the II subgroup on the “Physical Functioning” and “General Health” scores by 11.59 % (P = 0.039) and 15.98 % (P = 0.026) lower, respectively, compared to controls. More pronounces and significant decrease in quality of life was found in parameters of the psychological component, especially the “Vitality” and “Social functioning” scores were by 16.51 % (P = 0.021) and 23.12 % (P < 0.001) lower, respectively, compared to healthy women. The overall scores of quality of life were lower in persons of the II subgroup than in I. Conclusions. Decrease in quality of life is typical for women with PCOS. No significant difference was detected in the physical component score of quality of life between persons with PCOS and controls in the early reproductive age. Though, “Physical Functioning” and “General Health” scores were statistically lower in patients of active reproductive age compared to healthy individuals. However, a decrease in the psychological component of quality of life is typical for women with PCOS, especially for persons of the active reproductive age compared to those of the early one.
Highlights
Polycystic ovary syndrome (PCOS) is one of the most problematic neuroendocrine syndromes in gynecology
Decrease in quality of life is typical for women with PCOS
No significant difference was detected in the physical component score of quality of life between persons with PCOS and controls in the early reproductive age
Summary
The basic group consisted of 90 women with PCOS and was divided into the I and II subgroups. 60 women aged 18–25 years formed the I subgroup, 30 patients aged 26–35 years – the II one. 30 women without this pathology were controls. Diagnosis of PCOS was based on the Rotterdam criteria. Quality of life was assessed with the help of the 36-Item Short Form Health Survey. Diagnosis of PCOS was based on the Rotterdam criteria with the presence of two or three of the following ones: polycystic ovaries (at least 12 or more follicles or increased ovarian volume more than 10 cm3), oligo-ovulation or anovulation and clinical and/or biochemical signs of hyperandrogenism [8]. 60 women aged 18–25 years formed the I subgroup, 30 patients aged 26–35 years – the II one. Quality of life was studied with the help of the 36-Item Short Form Health Survey (SF-36)
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