Abstract
The study aims to determine whether the LDPI technique can provide an objective indication of synovial hyperaemia associated with inflamed finger joints. In addition, it hopes to obtain more information about the influence of pain and stiffness on the cutaneous blood flow and assess whether skin perfusion can be used as an index to evaluate these clinical parameters of Osteoarthritis.Except for the deformed joint, the red laser source (λ = 632.8 nm, visible red) failed to detect any hyperaemic areas associated with joint inflammation in patients with Osteoarthritis (OA). Measurements taken over the PIP joints of both groups have shown a good repeatability for all between-day measurements. However, the variation in between-day perfusion of the OA group is greater compared to the normal control. For majority of the subjects, perfusion in the adjacent skin tends to be lower and fluctuate less than that in their PIP joints. The study also indicates some correlation between the blood perfusion with pain and stiffness of the finger joints.Overall, the present finding suggests that a longer wavelength near-infrared laser have considerable potential for this form of imaging and that LDI can offer a convenient means of rapidly assessing an inflamed joint non-invasively. Further clinical studies in these areas are warranted.
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