Abstract
Ex vivo heart perfusion may facilitate resuscitation of non-utilized donor hearts. A reliable means of demonstrating organ viability prior to transplantation is required. Preload recruitable stroke work (PRSW) is a load independent metric of myocardial function obtained using a pressure-volume loop catheter; however, the expensive, cumbersome, and invasive nature of the equipment limits clinical translation. Therefore, we sought to develop a non-invasive method of measuring PRSW in an ex vivo, bi-ventricular, working heart device.
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