Assessment of potentially inappropriate medications in elderly according to Beers 2015 and STOPP criteria and their association with treatment satisfaction

Abstract

ObjectiveTo assess and compare, according to Beers and STOPP criteria, the frequency and causes of potentially inappropriate medications (PIMs) in elderly, as well as the relationship between PIMs use and patient’s treatment satisfaction, evaluated using the Treatment Satisfaction Questionnaire for Medications (TSQM). Method350 patients (mean age = 73.49 years), taking a total of 1893 medications, were enrolled from community pharmacies. Results6.2% and 20.4% of the medications were inappropriate according to the STOPP and Beers lists respectively; 103 (29.4%) and 210 (60%) patients had at least one PIM according to STOPP and Beers criteria respectively. The most common cause of PIM was a full dose of proton pomp inhibitor for >8 weeks (STOPP) and using a drug that exacerbates/causes syndrome of inappropriate antidiuretic hormone secretion (Beers). The number of medications taken by the participant, advanced age, female gender, prescription of medications for anxiety/depression, ulcers/gastroesophageal reflux, rheumatoid arthritis and epilepsy significantly increased the PIMs number.When using STOPP criteria, all TSQM subscale scores were significantly lower among patients with PIM use compared to those without PIM. The same trend was observed for Beers critertia, with a significant difference reached for side effects and convenience subscales only. ConclusionSelecting the appropriate tools to assess PIMs, prescribers and patient education regarding the risks associated with PIMs, and patient’s perception and satisfaction regarding his treatment, are critical issues to be addressed among older adults.