Abstract
BackgroundParkinson’s disease (PD) is a degenerative, progressive, neurological condition that influences the control of a person’s body movements. Computerized dynamic posturography (CDP) is a clinical tool intended to evaluate the integration of visual, vestibular, and somatosensory inputs to maintain postural gait. Posturography can be used to measure postural instability in PD patients. So, the aim of this study was to evaluate the postural control and elaborate on the pathophysiology of the balance impairment in PD patients in the “on” state.ResultsAll antero-posterior (AP) and medio-lateral (ML) sensory balance scores, except vestibular ones, were significantly lower in the study group compared to the control group. AP and ML sway were generally higher in the study group at all frequencies, with AP being mostly greater compared to ML sway in PD subjects. Global sensory scores were shown to deteriorate with increased durations of the disease and treatment.ConclusionsPD patients have higher postural instability in comparison to controls with AP sway being higher compared to ML.
Highlights
Parkinson’s disease (PD) is a degenerative, progressive, neurological condition that influences the control of a person’s body movements
A total number of 30 subjects were examined in this study, who were divided into a control group (15 subjects) and a study group (15 subjects)
All antero-posterior sensory balance scores, except vestibular, were lower in the study group compared to the control group
Summary
Parkinson’s disease (PD) is a degenerative, progressive, neurological condition that influences the control of a person’s body movements. Computerized dynamic posturography (CDP) is a clinical tool intended to evaluate the integration of visual, vestibular, and somatosensory inputs to maintain postural gait. The aim of this study was to evaluate the postural control and elaborate on the pathophysiology of the balance impairment in PD patients in the “on” state. Parkinson’s disease (PD) is a progressive and chronic degenerative CNS disorder. In 2013, there were up to 1,000,000 PD patients in the USA, and the prevalence is expected to reach double that number in 2040 [2]. The incidence of PD in USA is about 50,000 yearly [3]. Progression of the disease is associated with an abnormal gait called festination, characterized by lower speed and shorter
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